Photocatalytic α-arylation of cyclic ketones
WebNov 15, 2013 · The direct β-coupling of cyclic ketones with aryl ketones has been achieved via the synergistic combination of photoredox catalysis and organocatalysis. Diaryl oxymethyl or aryl–alkyl oxymethyl rad... WebJul 14, 2024 · Ketones serve as one of the most critical building blocks in organic synthesis, involving numerous functional group transformations. Herein, we report an unprecedented photoredox–nickel metallaphotoredox-catalyzed decarboxylative acylation of common aliphatic acids with readily available aromatic and aliphatic thioesters.
Photocatalytic α-arylation of cyclic ketones
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WebNov 22, 2013 · A photoredox-catalyzed umpolung strategy for coupling reactions between aldehydes, ketones, imines, and N-arylamines is reported. These reactions proceed by a Brønsted acid-activated proton-coupled… Expand 24 Reductive Arylation of Arylidene Malonates Using Photoredox Catalysis. Rick C. Betori, K. Scheidt Chemistry ACS catalysis … WebDOI: 10.1021/ja993912d ) has developed highly active and selective catalysts for the α-arylation of ketones. These consist of electron-rich phosphine ligands containing a biphenyl skeleton that are combined with the palladium complex …
WebEnantioselective α-Arylation of Ketones via a Novel Cu(I)–Bis(phosphine) Dioxide Catalytic System. Journal of the American Chemical Society 2024, 143 (9) , 3289-3294. WebEnantioselective α-Arylation of Ketones via a Novel Cu(I)–Bis(phosphine) Dioxide Catalytic System. Journal of the American Chemical Society 2024, 143 (9) , 3289-3294.
WebHighly E- and Z-Selective Hydrogenation of Alkynes Using Chromium and Cyclic Carbene Ligands Full Text HTML PDF (142 kb) ... –H Arylation in the γ-Position of Sulfamate Esters and Amides Full Text HTML ... Aldol-Type Reaction of α,α-Difluoromethyl Ketones Catalyzed by an Organosuperbase Full Text HTML PDF (88 kb) ... WebApr 12, 2024 · Phenols are important readily available synthetic building blocks and starting materials for organic synthetic transformations, which are widely found in agrochemicals, pharmaceuticals, and functional materials. The C–H functionalization of free phenols has proven to be an extremely useful tool in organic synthesis, which provides efficient …
WebAug 20, 2024 · The direct α-arylation of unactivated carbonyl compounds using aryl halides represents a powerful method to synthesize criti-cal building blocks for diverse useful …
phipps conservatory reservationsWebApr 6, 2024 · The versatility of the cyanation chemistry was later expanded to the asymmetric conjugate addition to α,β-unsaturated carbonyl compounds, including imides 10,11 and ketones 12,13,14. These ... tsp free cerealWebPhotocatalytic α-arylation of cyclic ketones @article{Hossain2024PhotocatalyticO, title={Photocatalytic $\alpha$-arylation of cyclic ketones}, author={M. Selim Hossain and … tsp freeWebFeb 3, 2024 · Here we report a green-light-mediated α-arylation of ketones from readily available aryl halides via activation of a C (sp2)–X bond (X = I, Br, Cl) and an α-carbonyl C … tsp full matchWebApr 10, 2024 · Aryl chlorides serve as both cross-coupling partners and the chlorine radical source for the α-oxy C(sp3)-H arylation of cyclic and acyclic ethers. Mechanistic studies suggest that photolysis of a Ni(III) aryl chloride intermediate, generated by photoredox-mediated single-electron oxidn., leads to elimination of a chlorine radical in what amts ... phipps conservatory reviewsWebPhotocatalysis is an advanced oxidation process that has received significant attention due to its low energy requirements and easy operation to break down the organic … tsp from 76WebMechanistic insights and a theoretical rationale that explains the ketone α-arylation versus dimerization selectivity are presented and moderate to good yields are obtained. An electrochemical procedure for the α-arylation of ketones has been developed. The method is based on the generation and one-pot anodic oxidation of silyl enol ethers in the … tsp free seminars